Pheomelanin-coated iron oxide magnetic nanoparticles: a promising candidate for negative T2 contrast enhancement in magnetic resonance imaging.

نویسندگان

  • Alexandre D A Zottis
  • Jeovandro M Beltrame
  • Luciano R S Lara
  • Thiago G Costa
  • Mateus J Feldhaus
  • Rozangela Curi Pedrosa
  • Fabiana Ourique
  • Carlos E M de Campos
  • Eduardo de A Isoppo
  • Fabio da Silva Miranda
  • Bruno Szpoganicz
چکیده

We describe herein a novel type of monodisperse water-soluble magnetite nanoparticle coated with pheomelanin using an environmentally-friendly approach in aqueous medium. The results indicate superparamagnetic behaviour at room temperature and show improved negative contrast in T2-weighted MRI with a transverse relaxivity of 218 mM(-1) s(-1).

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عنوان ژورنال:
  • Chemical communications

دوره 51 56  شماره 

صفحات  -

تاریخ انتشار 2015